Tyler William Warren Week 16 Preview vs. the 49ers

Indianapolis Colts receiver Tyler William Warren has a favorable matchup in Week 16 (Monday at 8:15 p.m. ET), playing the San Francisco 49ers. The 49ers are conceding the 10th-most passing yards in the NFL, 227.6 per game.

Tyler Warren's 90 targets have resulted in 63 grabs for 718 yards (51.3 per game) and four scores so far this season.

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Warren vs. the 49ers

• Warren vs the 49ers (since 2021): No games
• San Francisco has allowed 100 or more receiving yards to three opposing receivers in the 2025 season.
• The 49ers have allowed 24 opposing players to register a TD reception against them this year.
• Only one opposing player has caught at least two TD passes in matchups with San Francisco on the season.
• Warren will square off against the NFL's 23rd-ranked pass defense this week. The 49ers give up 227.6 passing yards per game.
• Opponents of the 49ers have scored 25 touchdowns through the air (1.8 per game). The 49ers' defense is 21st in the league in that category.

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Warren Receiving Insights

• In the receiving game, Warren has hit the over on his receiving yards prop bet in 42.9% of his games (six of 14).
• Warren has received 20.2% of his team's 445 passing attempts this season (90 targets).
• He has 718 receiving yards on 90 targets to rank 48th in NFL play with 8.0 yards per target.
• Tyler William Warren has four games with a touchdown catch this season (out of 14 played). He hasn't scored multiple touchdowns in any game.
• He has scored five of his team's 44 offensive touchdowns this season (11.4%).
• Warren has been targeted 16 times in the red zone (26.2% of his team's 61 red zone pass attempts).

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Warren's Recent Performance