Michael Pittman Jr. Week 16 Preview vs. the 49ers

Indianapolis Colts receiver Michael Pittman Jr. has a favorable matchup in Week 16 (Monday at 8:15 p.m. ET), playing the San Francisco 49ers. The 49ers are allowing the 10th-most passing yards in the NFL, 227.6 per game.

Pittman has caught 72 passes on 99 targets for 725 yards and seven scores. He averages 51.8 yards per game.

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Pittman vs. the 49ers

• Pittman vs the 49ers (since 2021): 1 GP / 105 REC YPG / 1 REC TD
• San Francisco has allowed three opposing receivers to pile up 100 or more receiving yards in a game in the 2025 season.
• 24 players have grabbed a TD pass against the 49ers this year.
• San Francisco has given up two or more TD receptions to just one opposing player on the season.
• The 227.6 passing yards per game given up by the 49ers defense makes them the NFL's 23rd-ranked pass defense.
• The 49ers' defense is 21st in the league by giving up 1.8 passing touchdowns per game to opponents (25 total passing TDs).

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Pittman Receiving Insights

• In the receiving game, Pittman has hit the over on his receiving yards prop bet in 42.9% of his games (six of 14).
• Pittman has been targeted on 99 of his team's 445 passing attempts this season (22.2% target share).
• He is averaging 7.3 yards per target (71st in NFL play), averaging 725 yards on 99 passes thrown his way.
• Pittman has seven games with a touchdown catch this year (out of 14 played). He hasn't scored multiple touchdowns in any game.
• He has scored seven of his team's 44 offensive touchdowns this season (15.9%).
• With nine red zone targets, Pittman has been on the receiving end of 14.8% of his team's 61 red zone pass attempts.

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Pittman's Recent Performance