Jonathan Taylor Week 16 Preview vs. the 49ers

Jonathan Taylor has a decent matchup when his Indianapolis Colts face the San Francisco 49ers in Week 16 (Monday, 8:15 p.m. ET). The 49ers have allowed 106.1 rushing yards per game, 12th in the league.

So far this year, Taylor has recorded a team-leading 1,443 rushing yards on 272 carries (103.1 ypg), while scoring 16 rushing TDs. In the passing game, he's also grabbed 38 balls for 318 yards (22.7 ypg) and two touchdowns.

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Taylor vs. the 49ers

• Taylor vs the 49ers (since 2021): 1 GP / 107 RUSH YPG / 1 RUSH TD
• Two opposing rushers have put up 100 or more rushing yards in a matchup against the 49ers during the 2025 season.
• San Francisco has given up one or more rushing TDs to eight opposing players this year.
• The 49ers have let just one opposing player to record two or more rushing TDs against them this season.
• Taylor will square off against the NFL's 12th-ranked rush defense this week. The 49ers allow 106.1 yards on the ground per contest.
• The 49ers have the No. 4 defense in the league in rushing TDs allowed, giving up nine this season (0.6 per game).

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Taylor Rushing Insights

• So far this season, Taylor has hit the over seven times on his rushing yards prop bet (in 14 opportunities).
• The Colts have passed 54.5% of the time and run 45.5% this season. They rank sixth in the NFL in scoring.
• He has carried the ball in 272 of his team's 372 total rushing attempts this season (73.1%).
• Taylor has scored at least one rushing touchdown seven times this year, inclduing multiple rushing TDs five times.
• He has 18 total touchdowns this season (40.9% of his team's 44 offensive TDs).
• He has 58 carries in the red zone (68.2% of his team's 85 red zone rushes).

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Taylor's Recent Performance